Tuesday, July 28, 2009


I want to know Puregon so I searched the internet and got this information. I have extracted few facts and posted it here. If you like to read the rest of the material just log on to:

www.betterhealth.vic.gov.au/...nsf/.../shcpureg.pdf -

Puregon solution for injection contains follitropin beta, a hormone known as follicle stimulating hormone (FSH).

FSH belongs to the group of gonadotrophins, which play an important role in human fertility and reproduction. FSH is needed in women for the growth and development of follicles in the ovaries.


Follicles are small round sacs that contain the egg cells.


Women:

* Puregon can be used to cause ovulation in women who have not responded to treatment with clomiphene citrate.

* Puregon can be used to bring about the development of multiple follicles in women undergoing assisted reproduction technologies (ART) such as in vitro fertilisation (IVF).


How is Puregon given:

The very first injection of Puregon should be given by a health professional. Puregon solution for injection in cartridges has been developed for use in the Puregon Pen. The separate instructions for using the pen must be followed carefully. Do not use the cartridge if the solution contains particles or if the solution is not clear.

Using the pen, injections just under the skin (in the stomach or thigh) can be given by you or your partner.

Your doctor will tell you when and how to do this. When the instructions are followed carefully, Puregon will be administered properly and with minimal discomfort.


How much to inject

Your doctor will decide on the dose of Puregon to be given. This dose may be adjusted as your treatment progresses. To find the right dosage, follicle growth is checked by means of ultrasound scanning and measurement of the amount of estradiol (female sex hormone) in blood or urine.


The following is a guide to the usual dose:


Women who are not ovulating

The dose usually starts at 75-150 IU daily. The dose is continued for at least 5 to 7 days. If there is no response, the daily dose will be gradually increased until an adequate response is obtained. The daily dose is then maintained until a follicle of adequate size is present.

An hCG injection (to stimulate ovulation) is given after the last Purgeon injection


Things you must not do

Do not stop using Puregon without telling your doctor.


Do not change the dose unless your doctor tells you to. Changing your dose without telling your doctor can increase your risk of unwanted side effects or can prevent the drug from working properly.


Do not give your medicine to anyone else, even if they have the same condition as you.



Storage

1. Store Puregon in the refrigerator (2 degrees C-8 degrees C). Do not freeze. Use until the expiry date printed on the label.

OR

2. Store at room temperature (at or below 25 degrees C) for a single period of not more than 3 months. Make a note of when you start storing Puregon out of the refrigerator.

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